Browse By

Best Mood Enhancing Supplements: Mood Effex Review is an independent review guide covering business and educational products and software. This website contains affiliate links and we may be compensated if you make a purchase after clicking these links.

Mood Effex is a dietary supplement made from natural (organic plants) ingredients that have been specially formulated to provide mood support.

In this in-depth review we will look at exactly how Mood Effex works, the ingredients it contains, and the kind of results you can expect if you are suffering from depression.

We will also look at whether there have been any known side effects, and the best way to take the supplements as part of your everyday diet.

Ready to be informed? Good, let’s get to it…


Check Best Deals on Mood Effex Supplements

Mood Effex
Natural Supplements
All Natural Ingredients
Mood Support
Reduce stress
Increase libido

What the Customers Say:

Mood Effex has been well received by the customers and medical experts alike. Both praise it for being packed with powerful natural ingredients that have proven can manage depression and stress.

Users have commended the product because it increases their state of mental alertness, while others value it for its libido-improving qualities. Also, customers praise it for a lack of side effects.

Mood Effex Reviewed – A Vault50 Analysis

The key to overall wellbeing is good physical and mental health. Mental health is vital to the overall health of a person because it not only promotes psychological wellbeing, but it also fosters physical wellbeing, especially in terms of accelerating physical recovery from acute illnesses.

Poor mental health can manifest itself physically as paralysis, fits, numbness, or even blindness; and this conversion of poor psychiatric health into poor physical health is called a conversion disorder.


Mental diseases are divided into groups, and the group of mental diseases with the highest prevalence rate today is a mood disorder.

Defined broadly, the mood disorder is a collective term that designates mental disorders that cause a disturbance in the mood of a person.

Mood disorders are broadly divided into 3; unhealthy elevated mood (called mania), depressed mood (called depression), and mood cycling between mania and depression (a condition termed bipolar disorder).

The most common mood disorder is depression. Depression can be difficult to treat using pharmaceutical drugs only, and this led to depression management evolving into a combination of pharmacotherapy (using drugs) and psychotherapy, a psychological-based modality of treatment.

Recently, dietary supplements have been introduced, and they can effectively manage depression.

One of the most effective dietary supplement for managing depression is Mood Effex, which is
recognized as one of the best natural mood enhancers, as well as one of the best mood-enhancing supplements.

Before we go in-depth with the Mood Effex review let’s first clarify what depression is.

What is depression?

Depression is a psychological state characterized by low mood and a general disinterest in activities, including those that previously pleasurable; and it negatively affects the behavior, thoughts, and feelings as well the general sense of well-being of the affected person.

The depressed mood can be transient(temporary) or sustained. Usually, a transient depressed mood due to loss or another catastrophic life event is considered a normal temporary reaction.

The common symptoms of depression

Depression causes the affected individual to be anxious, irritable, restless, and sad; as well as feel dejected, hopeless, worthless, and helpless; in addition to having a sense of guilt or extreme shame.

At this stage, the affected person loses interest in all activities, a condition called anhedonia; and is unable to concentrate, remember general facts, and experience relationship difficulties.

Other symptoms include insomnia (sleeplessness or inability to fall asleep), hypersomnia (excessive sleeping and excessive sleepiness), fatigue and somatic (or physical) symptoms such as maldigestion, aches, and localized pain.

Expectedly, the decision making ability of the depressed individual is impaired and she/he can contemplate suicide.

Causes of Depression

Depression is caused by a multitude of factors which are described hereafter.

To begin with, traumatic life events such as catastrophic physical injury (for instance limb loss),
bereavement, childhood neglect, sexual abuse, stress, financial difficulties (including bankruptcy), mental abuse, bullying, physical abuse, social isolation, and social rejection can cause one to be

The second factor relates to personality as people exhibiting neuroticism and high introversion are more prone to developing depression as compared to people of other personality

This is mainly due to their poor response to life stressors (traumatic events) and their inclination to interpret such stressors are hopelessly difficult challenges.

Drug-induced depression

Depression can also be caused by medical treatment, and this form of drug-induced depression is termed iatrogenic depression.

Implicated drugs include cardiac agents, interferon, hormonal contraceptives, anticonvulsants, antipsychotics, isotretinoin, and anti-migraine drugs.

Substance abuse can also cause depression, and this substance-induced depression can be exacerbated by either intoxication or withdrawal.

The main drugs of abuse that cause substance-induced depression are cocaine, amphetamines, hallucinogens, heroin, alcohol, inhalants, sedatives such as benzodiazepines, and opioids (including opioid analgesics such as Tramadol, Fentanyl, and Methadone).

Psychiatric syndromes and non-psychiatric diseases

Depression can also be caused by both psychiatric syndromes and non-psychiatric diseases. The main non-psychiatric illnesses that can trigger depression are nutritional deficiencies, hormonal disorders, chronic pain, infectious diseases, Parkinson’s disease, diabetes, stroke, neurological conditions, and cancer.

Regarding psychiatric syndromes, all psychiatric disorders that affect the mood are liable to cause depression, with some disorders presenting with depression as the chief symptom.

Depression can feature in adjustment disorders and anxiety disorders such as post-traumatic stress disorder(PTSD).

Clinical and Chronic depression

Among the mood disorders, there is a classification called clinical depression.

Clinical depression, also called major depression or major depressive disorder (MDD) presents with depression as the predominant symptom with the individual experiencing anhedonia and a depressed mood for more than 2 weeks.

A closely related condition is Major Depressive Episode (MDE) where a depressed mood and anhedonia persist for 2 weeks.

If the depressive episodes follow (that is, changes with) seasonal patterns, then the condition is called Seasonal Affective Disorder(SAD).

Chronic depression that is less severe than either MDD or MDE, and lasts for 2 years is called

Depression can be classified based on its severity/intensity into 3 broad groups: mild, moderate, and severe.

Mild depression presents with a depressed mood along with other symptoms of depression, and only lasts for a few days and hence does not affect self-esteem or cause a significant decrease in productivity.

Moderate depression presents with all the symptoms of mild depression along with low self-esteem and reduced productivity and lasts for only a few weeks.

Severe depression presents with the symptoms of MDD and it can incapacitate the individual by making him unproductive and suicidal, and it lasts for more than 6 months.

The pathophysiology and biochemistry of depression

There is also a need to describe the pathophysiology and biochemistry of depression.

The exact bio-mechanism that leads to the development of depression is not exactly known currently, but there are theories that attempt to explain its pathogenesis.

One of these theories is the monoaminergic theory which postulates that depression develops when the main neurotransmitter, collectively called monoamines, that is used in the monoaminergic neuronal pathway in the brain is in short supply.

One of the main monoamine transmitters is serotonin which is usually depleted in the CNS (central nervous system) of depressed people.

The other 2 monoamines whose physiological imbalance in the brain is theorized to cause depression are norepinephrine (noradrenaline) and dopamine.

Treatment of depression

Not all forms of depression require professional treatment, especially iatrogenic depression and substance-induced depression which can be managed by withdrawing the depression-triggering drugs.

Severe depression can be managed through combined therapy that includes anti-depressant medications and psychotherapy.

Even so, a study published in 2016 by The Lancet showed that most antidepressant medications, with the exception of Fluoxetine, are not totally effective in managing childhood and adolescent MDD.

Depression can also be managed by dietary supplements. One of the best supplements for managing depression is Mood Effex.

Mood Effex Review

Mood Effex is a specially formulated natural supplement that can be used to manage mild depression, as well as some forms of moderate depression.

It is made entirely of natural organic herbs that have been carefully and hygienically prepared to create a potent dietary supplement that can relieve mild depression, reduce stress, enhance mental alertness, improve libido, and promote proper blood circulation in the body, especially increasing the rate of blood flow to vital organs such as brains, liver, and kidneys.

Regardless, how does Mood Effex work to cause these therapeutic body changes?

How Does Mood Effex Work

Mood Effex works to alleviate depression primarily by increasing serotonin levels in the human brain.

Still, the therapeutic value of Mood Effex rests on the active ingredients of its composite herbs.

It is the active ingredients in each of these herbs that give Mood Effex its combined therapeutic power, and for this reason, the active ingredients of each herb are described below in relation to how the supplement works in the body.

Tribulus Terrestris

Tribulus Terrestris is a plant native to Asia and the Americas and has been used as a medicinal herb in traditional Indian and Chinese medicine.

When used as a dietary supplement, Tribulus Terrestris extracts cause an increase in the production of the male hormone, testosterone, as well as stimulates androgen receptors located in the brain, thus achieving a net effect of increasing sexual libido and promoting the overall male sexual health.

Moreover, its hydroalcoholic extract can propel urinary stones out of the body by evoking contractile actions in the ureter which pushes the stones to the bladder from where they
leave the body via the urethra.

This herb also improves sexual libido in sexually hypoactive (less active) women.

Morinda Officinalis

Morinda Officinalis is a plant native to Asia and has been used as a medicinal herb in traditional Indian and Chinese medicine.

Its root contains 5 main pharmacologically active compounds; anthraquinones, a ursane-type triterpene, iridoid glucosides, sterols, and an iridoid lactone compound.

These 5 compounds exhibit strong antidepressant activities as they work synergistically to alleviate the symptoms of mild depression.

The glucosides and lactone compounds show a strong anti-fatigue effect which alleviates anhedonia. It also increases the level of mental alertness. The root extract evokes a sense of euphoria which helps to turn a depressed mood into a happy mood.

Nardostachys chinensis

Nardostachys Chinensis is an aromatic plant with rhizome roots that is native to Asia and has been used as a medicinal herb in traditional Indian and Chinese medicine.

It contains pharmacologically-active phytochemicals including Valeranone which is a sedative that manages the restlessness and insomnia associated with depression. Its volatile aromatic oil evokes a sense of euphoria which helps to turn a depressed mood into a happy mood.

St. Johns Wort

St. Johns Wort, also called Hypericum perforatum, is a medicinal herb that has been used since classical antiquity to manage depression, including clinical depression.

Its oil extract contains 2 active ingredients; hypericin and hyperforin.

Hyperforin has both anxiolytic (anxiety-alleviating or stress-relieving) and antidepressant properties owing to its inhibition of monoamines reuptake which ensures that a high concentration of monoamine transmitters are available to act on neurons of the monoaminergic systems in the CNS.

It inhibits the reuptake of serotonin, norepinephrine, and dopamine hence allowing them to act on CNS neurons for a longer time. Clinical depression is associated with very low levels of serotonin in the CNS/brain, and by increasing the CNS serotonin concentration, hyperforin alleviates clinical depression.

On the other hand, hypericin is an anthraquinone derivative that inhibits the action of an enzyme called dopamine β-hydroxylase which metabolizes dopamine into an inactive ingredient.

By inhibiting this enzyme, Hypericin ensures that the dopamine levels in the CNS remain high which stabilizes the functions and actions of dopaminergic neurons.

Less active dopaminergic neurons trigger depression while fully active dopaminergic neurons alleviate depression, including mild to moderate depression.

The highly potent and efficacious antidepressant properties of St. Johns Wort makes it the main herb that manages depression in Mood Effex.

Cyperus Rotundus

Cyperus Rotundus is a plant native to Africa, South Asia, and Central Europe and has been used as a medicinal herb in these areas.

Its root extract contains the active ingredient, a sesquiterpene called rotundone which exhibits strong anti-oxidant properties. The root extract also causes vasodilation which improves blood flow to vital body organs.

Albizia Julibrissin

Albizia Julibrissin. also called Persian silk tree, is a plant native to Eastern and Southwestern Asia, and its durazz flower has been used in herbal medicinals to manage depression.

The flower contains methylene chloride as its active ingredient. methylene chloride exhibits the strong antidepressant effect and acts on serotonin receptors where it stimulates them to be active.

Angelica Sinensis

Angelica Sinensis is a plant native to China and features in Chinese traditional medicine. Its root extract contains the active ingredient butylidenephthalide which is a strong antispasmodic compound that also exhibits antidepressant-like effects.

It allows stiff muscles to relax which aids digestion as well as elicit a calming sensation in
the user.

It also allows vasoconstriction blood vessels to relax hence improving blood flow throughout the body.

How to Use Mood Effex to Achieve Optimal Results?

Mood Effex is formulated by CLE Holistic Health Ltd, and it comes in a container that contains 60 capsules.

These capsules are made from vegetable extracts which makes it easy for the body to digest capsule and release the capsule contents in the alimentary canal. It is recommended that one takes 2 capsules per serving.

This serving can be taken alongside food or before food is eaten. It is better to take the serving on an empty stomach as this allows the body to quickly digest the capsule and rapidly absorb the natural ingredients contained therein.

This ultimately allows the active ingredients of the natural supplements to reach their target sites/organs quickly where they produce their desired effect within a short time.

One should take a single serving per day for 30 consecutive days.

Does Mood Effex have Side Effects?

Mood Effex is a dietary supplement made of natural organic compounds extracted from plants.

As such it is digested, absorbed, and assimilated in the body just as any ordinary plant meal, and it causes no known side effect.

However, you should always consult your medical practitioner if you are already taking prescribed medication and wish to use Mood Effex alongside other drugs.

Benefits of using Mood Effex

Mood Effex is a potent and effective natural supplement for managing mild to moderate depression.

It can also be used in conjunction with pharmacotherapy and psychotherapy to manage severe depression.

Mood Effex also has anxiolytic properties which enable it to reduce stress. Its antidepressant and anxiolytic properties work together to promote happiness, elicit joy, and better the overall health of the user.

Likewise, it improves the state of mental alertness and improves cognitive awareness.

Another benefit of Mood Effex is that it improves sexual libido as well as improves blood circulation in the body. This ultimately enables the body to restore its physiological balance.